Spaying for female dogs is an ovariohysterectomy, a procedure that removes the ovaries and uterus. Based on veterinary textbooks, we’ve compiled essential information for pet owners, covering everything from pre-surgical preparation to post-operative care.

| Timing | Characteristics | Notes |
|---|---|---|
| Before the first heat | Maximizes prevention of mammary tumors | Recommended timing per veterinary textbooks |
| After the first heat | Preventive effect decreases, but surgery is still possible | Recommended during the resting phase (anestrus) after heat ends |
| Large breeds | Optimal timing varies by size and breed | Consultation with your veterinarian is essential |

Be sure to check these before surgery
During estrus, estrogen causes increased blood flow to the reproductive and mammary tissues and weakens the uterine tissue, making it prone to tearing when manipulated with surgical instruments and thereby raising the risk of intraoperative bleeding. Therefore, spaying is typically performed during the anestrus (resting) phase after estrus has ended for safety. Additionally, if your puppy has not completed its vaccinations, please review the vaccination schedule first. A preoperative health assessment must always be conducted together with your attending veterinarian.


Weight management is important after surgery
After neutering, hormonal changes reduce your pet’s basal metabolic rate. According to veterinary textbooks, even if you feed the same amount as before surgery, your pet will be in a state where weight gain is more likely. Since obesity can increase the risk of various health issues, please consult your veterinarian after surgery to appropriately adjust the feeding amount and regularly monitor your pet’s weight.

A veterinarian who majored in veterinary medicine at Khon Kaen University, Thailand, and completed the IVSA program at North Carolina State University in the United States. Drawing on clinical experience at animal hospitals, he works in the pet healthcare field and is dedicated to building a digital care environment that connects pet parents with veterinarians.
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[1] Handbook on Field Veterinary Surgery — Ch19: Ovariohysterectomy in Canines and Felines - Surgical Procedure
[2] The Dog Care Handbook, Things I Wish My Vet Had Told Me — Neutering section
[3] The Cat, Clinical Medicine and Management, 2nd Edition — Chapter: Population Control and Neutering
[4] Veterinary Surgery: Small Animal (Tobias & Johnston) — Ovariohysterectomy