We’ve put together a clear overview of how catnip works, the percentage of cats that respond to it, how it differs from alternative plants like silver vine and valerian, and how to use it safely.



Stop for a Moment If You See These Reactions
Catnip is generally a non-toxic and safe herb, but it can cause overexcitement or aggressive behavior in some cats. If you notice such reactions, remove the catnip immediately and help your cat calm down in a quiet space. For cats with underlying health conditions or specific medical concerns, it’s best to consult your veterinarian before introducing any new stimuli or plants.

| Item | Catnip | Silvervine (matatabi) | Valerian | Tatarian honeysuckle |
|---|---|---|---|---|
| Response rate | About 68% | About 80% | About 50% | About 50% |
| Main compound | Nepetalactone | Actinidine, dihydroactinidiolide | Actinidine | Nepetalactol |
| Duration | 5–15 min | 5–30 min | 5–15 min | 5–15 min |
| Main form | Dried leaves, spray | Sticks, powder | Root powder | Wood chips |
| Alternative for catnip-nonresponsive cats | False | True | True | True |
Based on the response rate of 100 cats in Bol et al., BMC Veterinary Research (2017)

Checkpoints for Choosing Catnip Toys
When selecting catnip toys, choose ones with thick, durable fabric and strong stitching to prevent the filling from spilling out and posing a choking hazard if the toy tears. Products with 100% catnip content tend to retain their scent longer, while refillable toys that come with catnip powder refills offer a more economical option. As for maintenance, replace the toy immediately if it becomes severely worn or if the inner lining is exposed.

A veterinarian who majored in veterinary medicine at Khon Kaen University, Thailand, and completed the IVSA program at North Carolina State University in the United States. Drawing on clinical experience at animal hospitals, he works in the pet healthcare field and is dedicated to building a digital care environment that connects pet parents with veterinarians.
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[1] Rodan I., Heath S., Feline Behavioral Health and Welfare, Elsevier, 2016
[2] Bol S. et al., Responsiveness of cats to silver vine, Tatarian honeysuckle, valerian and catnip, BMC Veterinary Research, 2017
[3] Little S.E., The Cat: Clinical Medicine and Management, 2nd Edition, Elsevier, 2020