We’ve compiled the essentials every pet owner should know—from pre-trip preparations to veterinarian-prescribed medications—into a Q&A format to help you distinguish why your cat is trembling in the car and identify signs of motion sickness.

| Item | Fear/anxiety symptoms | Motion sickness symptoms |
|---|---|---|
| Behavior | Trembling, hiding, loud vocalizing | Lethargy, crouching motionless |
| Digestive | Reduced appetite | Drooling, vomiting, retching foam |
| Physical | Dilated pupils, whiskers laid back | Nausea, frequent swallowing of saliva |
| Onset timing | From the moment the carrier is brought out | Within a few minutes after the car starts moving |
| Main cause | Past negative experiences, unfamiliar environment | Overstimulation of the vestibular system, visual stimulation |
The two sets of symptoms often appear at the same time.

Go to a Veterinary Clinic Immediately If These Symptoms Appear
If vomiting persists repeatedly, or if extreme lethargy and panting continue for more than two hours after travel has ended, it may not be simple motion sickness or stress. In particular, breathing with an open mouth is an emergency sign. You should go to a veterinary clinic immediately.


Do Pheromone Products Work?
Spraying a feline calming pheromone (such as Feliway) inside the carrier before travel can help reduce anxiety in some cats. However, you must ventilate the carrier for at least 15 to 20 minutes after spraying before placing your cat inside. This approach does not work equally well for all cats.

A veterinarian who majored in veterinary medicine at Khon Kaen University, Thailand, and completed the IVSA program at North Carolina State University in the United States. Drawing on clinical experience at animal hospitals, he works in the pet healthcare field and is dedicated to building a digital care environment that connects pet parents with veterinarians.
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[1] Rodan I, Heath S. Handling the Cat that is in Pain. In: Rodan I, Heath S, editors. Feline Behavioral Health and Welfare: Prevention and Treatment. Elsevier, 2016.
[2] Little SE, editor. The Cat: Clinical Medicine and Management. 2nd ed. Elsevier Saunders, 2012. Chapter: Transporting the Cat to the Veterinary Practice.
[3] Amat M, Camps T, Manteca X. Stress in owned cats: Behavioural changes and welfare implications. Journal of Feline Medicine and Surgery. 2016;18(8):577-586.
[4] Bowen J, Heath S. Behaviour Problems in Small Animals: Practical Advice for the Veterinary Team. Elsevier Saunders, 2005.